Medical Biostatistics Blog & Guides

Series Category 1

Medical Biostatistics & Data Analysis

4 Comprehensive Guides

Decision Framework 8 Min Read

How to Choose the Right Statistical Test for Your Clinical Study (Flowchart Guide)

A practical clinician's decision guide covering nominal, ordinal, and continuous variables, normality testing (Shapiro-Wilk vs Kolmogorov-Smirnov), parametric vs non-parametric equivalents, and multivariable regression models.

#SPSS #t-test #ANOVA #MannWhitney

Dr. Manjinder Singh Sidhu

Lead Author

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Sample Sizing 9 Min Read

Demystifying Sample Size Calculation in Medical Research: Why "N" Matters

The 4 pillars of power calculation (Alpha, Power 1-Beta, Effect Size, and Variance), clinical prevalence formulas, comparing two independent means, and adjusting for loss to follow-up before ethics committee submission.

#SampleSize #PowerAnalysis #GPower #IECApproval

Dr. Manjinder Singh Sidhu

Lead Author

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Survival Analysis 10 Min Read

Survival Analysis 101: Kaplan-Meier Curves & Cox Proportional Hazards

A deep dive into time-to-event outcomes, right censoring, step-down Kaplan-Meier curve construction, Log-Rank testing, Hazard Ratios (HR), and testing proportional hazards assumptions in oncology and surgical trials.

#KaplanMeier #CoxRegression #HazardRatio #Oncology

Dr. Manjinder Singh Sidhu

Lead Author

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Diagnostics 8.5 Min Read

ROC Curves & Diagnostic Test Accuracy: Sensitivity, Specificity, and AUC

How to construct and interpret ROC curves for novel biomarkers and screening tests, evaluate AUC (C-statistic), determine optimal cutoffs via Youden's Index (J), and comply with STARD 2015 reporting guidelines.

#ROCCurve #AUC #YoudensIndex #STARD2015

Dr. Manjinder Singh Sidhu

Lead Author

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Medical Biostatistics & Academic Guides

Dr. Manjinder Singh Sidhu

Medical Biostatistics & Data Analysis

How to Choose the Right Statistical Test for Your Clinical Study (Flowchart Guide)

Demystifying Sample Size Calculation in Medical Research: Why "N" Matters

Survival Analysis 101: Kaplan-Meier Curves & Cox Proportional Hazards

ROC Curves & Diagnostic Test Accuracy: Sensitivity, Specificity, and AUC

Need Professional Biostatistics & Research Support?